Intracellular magnesium content changes during mitochondria-mediated apoptosis: in depth study of early events on mitochondrial membrane potential

A recent study showed the antitumor activity of a new indole-derivative – MM-67 – inducing mitochondria-mediated apoptosis and a decrease of intracellular magnesium (Mg) concentration in HT29 colon cancer cells. Aim of this work was to assess cellular Mg levels throughout MM-67-i...

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Bibliographic Details
Main Authors: Lucia Merolle, Concettina Cappadone, Giovanna Farruggia, Chiara Marraccini, Azzurra Sargenti, Alessia Colanardi, Stefano Iotti
Format: Article
Language:English
Published: PAGEPress Publications 2014-01-01
Series:Journal of Biological Research
Subjects:
Online Access:http://www.pagepressjournals.org/index.php/jbr/article/view/2139