Cell aggregation induces phosphorylation of PECAM-1 and Pyk2 and promotes tumor cell anchorage-independent growth

<p>Abstract</p> <p>Background</p> <p>Apoptosis caused by inadequate or inappropriate cell-matrix interactions is defined as anoikis. Although transformed cells are known to be anoikis-resistant, the underlying mechanisms have not been well understood. We investigated th...

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Bibliographic Details
Main Authors: Yu Qiang, Xu Li-hua, Zhang Xing
Format: Article
Language:English
Published: BMC 2010-01-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/7