Zwitterionically modified alginates mitigate cellular overgrowth for cell encapsulation

Zwitterionically modified alginates mitigate cellular overgrowth for cell encapsulation

Cellular overgrowth and fibrosis in the foreign body response can compromise the function of transplanted cells. Here, the authors report on the zwitterionically modified alginates for the encapsulation of cells to reduce cellular overgrowth and demonstrate application in mice, dogs and pigs.

Bibliographic Details
Main Authors: Qingsheng Liu, Alan Chiu, Long-Hai Wang, Duo An, Monica Zhong, Alexandra M. Smink, Bart J. de Haan, Paul de Vos, Kevin Keane, Andreas Vegge, Esther Y. Chen, Wei Song, Wendy F. Liu, James Flanders, Claude Rescan, Lars Groth Grunnet, Xi Wang, Minglin Ma
Format: Article
Language:English
Published: Nature Publishing Group 2019-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13238-7

Internet

https://doi.org/10.1038/s41467-019-13238-7

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