A rapid change in virulence gene expression during the transition from the intestinal lumen into tissue promotes systemic dissemination of Salmonella.

Bacterial pathogens causing systemic disease commonly evolve from organisms associated with localized infections but differ from their close relatives in their ability to overcome mucosal barriers by mechanisms that remain incompletely understood. Here we investigated whether acquisition of a regula...

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Bibliographic Details
Main Authors: Sebastian E Winter, Maria G Winter, Ivan Godinez, Hee-Jeong Yang, Holger Rüssmann, Helene L Andrews-Polymenis, Andreas J Bäumler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2924370?pdf=render