TLR-4 and CD14 Genotypes and Soluble CD14: Could They Predispose to Coronary Atherosclerosis?

TLR-4 and CD14 Genotypes and Soluble CD14: Could They Predispose to Coronary Atherosclerosis?

Background: Inflammatory mechanisms are key to the pathogenesis of atherosclerosis. Functional polymorphisms of TLR-4, Asp299Gly and Thr399Ile, CD14 promoter area C260T polymorphism and plasma levels of soluble CD14 are studied in subjects with Coronary Artery Disease (CAD). Methods: DNA was obtaine...

Full description

Bibliographic Details
Main Authors: Maria Kalliopi Konstantinidou, Nikos Goutas, Dimitrios Vlachodimitropoulos, Antigoni Chaidaroglou, Demetrios Stefanou, Nikoleta Poumpouridou, Renata Mastorakou, Maria Gazouli, Dimitrios Kyparissopoulos, Chara Spiliopoulou
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
coronary atheroscerosis
coronary artery disease
Toll-Like-Receptor 4 (TLR-4)
CD14
sCD14
PCR-RFLP
ELISA
Online Access:http://www.mdpi.com/2308-3425/3/1/9

Internet

http://www.mdpi.com/2308-3425/3/1/9

Similar Items