Serum microRNA-1 and microRNA-133a levels reflect myocardial steatosis in uncomplicated type 2 diabetes

Abstract Using in vitro, in vivo and patient-based approaches, we investigated the potential of circulating microRNAs (miRNAs) as surrogate biomarkers of myocardial steatosis, a hallmark of diabetic cardiomyopathy. We analysed the cardiomyocyte-enriched miRNA signature in serum from patients with we...

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Bibliographic Details
Main Authors: D. de Gonzalo-Calvo, R. W. van der Meer, L. J. Rijzewijk, J. W. A. Smit, E. Revuelta-Lopez, L. Nasarre, J. C. Escola-Gil, H. J. Lamb, V. Llorente-Cortes
Format: Article
Language:English
Published: Nature Publishing Group 2017-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-00070-6