Factor VIII: Perspectives on Immunogenicity and Tolerogenic Strategies

Therapeutic treatment of bleeds with FVIII can lead to an antibody response that effectively inhibits its function. Herein, we review the factors that contribute to this immunogenicity and possible ways to overcome it.

Bibliographic Details
Main Authors: David W. Scott, Kathleen P. Pratt
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.03078/full