Interactions between blood-borne Streptococcus pneumoniae and the blood-brain barrier preceding meningitis.

Streptococcus pneumoniae (the pneumococcus) is a Gram-positive bacterium and the predominant cause of bacterial meningitis. Meningitis is thought to occur as the result of pneumococci crossing the blood-brain barrier to invade the Central Nervous System (CNS); yet little is known about the steps pre...

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Bibliographic Details
Main Authors: Federico Iovino, Carlos J Orihuela, Henk E Moorlag, Grietje Molema, Jetta J E Bijlsma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3713044?pdf=render