Circulating Histones in Sepsis: Potential Outcome Predictors and Therapeutic Targets

Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection and is associated with high morbidity and mortality. Circulating histones (CHs), a group of damage-associated molecular pattern molecules mainly derived from neutrophil extracellular traps,...

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Bibliographic Details
Main Authors: Yupei Li, Dingyuan Wan, Xinyao Luo, Tao Song, Yiran Wang, Qiao Yu, Luojia Jiang, Ruoxi Liao, Weifeng Zhao, Baihai Su
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.650184/full