Gene Tree Affects Inference of Sites under Selection by the Branch-Site Test of Positive Selection

The branch-site test of positive selection is a standard approach to detect past episodic positive selection in a priori-specified branches of a gene phylogeny. Here, we ask if differences in the topology of the gene tree have any influence on the ability to infer positively selected sites. Using si...

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Bibliographic Details
Main Authors: Yoan Diekmann, José B. Pereira-Leal
Format: Article
Language:English
Published: SAGE Publishing 2015-01-01
Series:Evolutionary Bioinformatics
Online Access:https://doi.org/10.4137/EBO.S30902