The Genome of C57BL/6J “Eve”, the Mother of the Laboratory Mouse Genome Reference Strain

The Genome of C57BL/6J “Eve”, the Mother of the Laboratory Mouse Genome Reference Strain

Isogenic laboratory mouse strains enhance reproducibility because individual animals are genetically identical. For the most widely used isogenic strain, C57BL/6, there exists a wealth of genetic, phenotypic, and genomic data, including a high-quality reference genome (GRCm38.p6). Now 20 years after...

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Bibliographic Details
Main Authors: Vishal Kumar Sarsani, Narayanan Raghupathy, Ian T. Fiddes, Joel Armstrong, Francoise Thibaud-Nissen, Oraya Zinder, Mohan Bolisetty, Kerstin Howe, Doug Hinerfeld, Xiaoan Ruan, Lucy Rowe, Mary Barter, Guruprasad Ananda, Benedict Paten, George M. Weinstock, Gary A. Churchill, Michael V. Wiles, Valerie A. Schneider, Anuj Srivastava, Laura G. Reinholdt
Format: Article
Language:English
Published: Oxford University Press 2019-06-01
Series:G3: Genes, Genomes, Genetics
Subjects:
reproducibility
reference genomes
de novo genome assembly
long read sequencing
laboratory mouse
C57BL/6J
Mus musculus domesticus
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.119.400071

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http://g3journal.org/lookup/doi/10.1534/g3.119.400071

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