Experimental and natural evidence of SARS-CoV-2-infection-induced activation of type I interferon responses

Experimental and natural evidence of SARS-CoV-2-infection-induced activation of type I interferon responses

Summary: Type I interferons (IFNs) are our first line of defense against virus infection. Recent studies have suggested the ability of SARS-CoV-2 proteins to inhibit IFN responses. Emerging data also suggest that timing and extent of IFN production is associated with manifestation of COVID-19 severi...

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Bibliographic Details
Main Authors: Arinjay Banerjee, Nader El-Sayes, Patrick Budylowski, Rajesh Abraham Jacob, Daniel Richard, Hassaan Maan, Jennifer A. Aguiar, Wael L. Demian, Kaushal Baid, Michael R. D'Agostino, Jann Catherine Ang, Tetyana Murdza, Benjamin J.-M. Tremblay, Sam Afkhami, Mehran Karimzadeh, Aaron T. Irving, Lily Yip, Mario Ostrowski, Jeremy A. Hirota, Robert Kozak, Terence D. Capellini, Matthew S. Miller, Bo Wang, Samira Mubareka, Allison J. McGeer, Andrew G. McArthur, Andrew C. Doxey, Karen Mossman
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:iScience
Subjects:
Immunology
Virology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221004454

Internet

http://www.sciencedirect.com/science/article/pii/S2589004221004454

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