Low dose pramipexole is neuroprotective in the MPTP mouse model of Parkinson's disease, and downregulates the dopamine transporter via the D<sub>3 </sub>receptor
<p>Abstract</p> <p>Background</p> <p>Our aim was to determine if pramipexole, a D<sub>3 </sub>preferring agonist, effectively reduced dopamine neuron and fiber loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model when given at intraper...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2004-10-01
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| Series: | BMC Biology |
| Online Access: | http://www.biomedcentral.com/1741-7007/2/22 |