Driver Mutations and Single Copy Number Abnormalities Identify Binet Stage A Patients with Chronic Lymphocytic Leukemia with Aggressive Progression

Driver Mutations and Single Copy Number Abnormalities Identify Binet Stage A Patients with Chronic Lymphocytic Leukemia with Aggressive Progression

The correlation between progression and the genetic characteristics of Binet stage A patients with chronic lymphocytic leukemia (CLL) detected by whole exome sequencing (WES) was analyzed in 55 patients. The median follow-up for the patients was 102 months. During the follow-up, 24 patients (43%) pr...

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Bibliographic Details
Main Authors: Ana P Gonzalez-Rodriguez, Angel R. Payer, Juan J Menendez-Suarez, Christian Sordo-Bahamonde, Seila Lorenzo-Herrero, Joud Zanabili, Ariana Fonseca, Ana Julia Gonzalez-Huerta, Pilar Palomo, Segundo Gonzalez
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Journal of Clinical Medicine
Subjects:
chronic lymphocytic leukemia
Binet
next-generation sequencing
whole exome sequencing
genetics
mutation
Online Access:https://www.mdpi.com/2077-0383/9/11/3695

Internet

https://www.mdpi.com/2077-0383/9/11/3695

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