Food perception without ingestion leads to metabolic changes and irreversible developmental arrest in C. elegans

Abstract Background Developmental physiology is very sensitive to nutrient availability. For instance, in the nematode Caenorhabditis elegans, newly hatched L1-stage larvae require food to initiate postembryonic development. In addition, larvae arrested in the dauer diapause, a non-feeding state of...

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Bibliographic Details
Main Authors: Rebecca E. W. Kaplan, Amy K. Webster, Rojin Chitrakar, Joseph A. Dent, L. Ryan Baugh
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Biology
Subjects:
IGF
Online Access:http://link.springer.com/article/10.1186/s12915-018-0579-3