Calpain Activity Is Generally Elevated during Transformation but Has Oncogene-Specific Biological Functions
Several oncogene and tumor-suppressor gene products are known substrates for the calpain family of cysteine proteases, and calpain is required for transformation by v-src and tumor invasion. Thus, we have now addressed whether calpain is generally associated with transformation and how calpain cont...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2004-01-01
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Series: | Neoplasia: An International Journal for Oncology Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558604800538 |