Calpain Activity Is Generally Elevated during Transformation but Has Oncogene-Specific Biological Functions

Several oncogene and tumor-suppressor gene products are known substrates for the calpain family of cysteine proteases, and calpain is required for transformation by v-src and tumor invasion. Thus, we have now addressed whether calpain is generally associated with transformation and how calpain cont...

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Bibliographic Details
Main Authors: N.O. Carragher, B.D. Fonseca, M.C. Frame
Format: Article
Language:English
Published: Elsevier 2004-01-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558604800538