Cholesterol Homeostasis Modulates Platinum Sensitivity in Human Ovarian Cancer

Cholesterol Homeostasis Modulates Platinum Sensitivity in Human Ovarian Cancer

Despite initial chemotherapy response, ovarian cancer is the deadliest gynecologic cancer, due to frequent relapse and onset of drug resistance. To date, there is no affordable diagnostic/prognostic biomarker for early detection of the disease. However, it has been recently shown that high grade ser...

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Bibliographic Details
Main Authors: Daniela Criscuolo, Rosario Avolio, Giovanni Calice, Chiara Laezza, Simona Paladino, Giovanna Navarra, Francesca Maddalena, Fabiana Crispo, Cristina Pagano, Maurizio Bifulco, Matteo Landriscina, Danilo Swann Matassa, Franca Esposito
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cells
Subjects:
ovarian cancer
TRAP1
cholesterol homeostasis
platinum resistance
Online Access:https://www.mdpi.com/2073-4409/9/4/828

Internet

https://www.mdpi.com/2073-4409/9/4/828

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