Tetradecanoic Acids With Anti-Virulence Properties Increase the Pathogenicity of Pseudomonas aeruginosa in a Murine Cutaneous Infection Model

Tetradecanoic Acids With Anti-Virulence Properties Increase the Pathogenicity of Pseudomonas aeruginosa in a Murine Cutaneous Infection Model

Blocking virulence is a promising alternative to counteract Pseudomonas aeruginosa infections. In this regard, the phenomenon of cell-cell communication by quorum sensing (QS) is an important anti-virulence target. In this field, fatty acids (FA) have gained notoriety for their role as autoinducers,...

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Bibliographic Details
Main Authors: Martha María Juárez-Rodríguez, Humberto Cortes-López, Rodolfo García-Contreras, Bertha González-Pedrajo, Miguel Díaz-Guerrero, Mariano Martínez-Vázquez, José Alberto Rivera-Chávez, Ramón Marcos Soto-Hernández, Israel Castillo-Juárez
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
anti-virulence activity
saturated fatty acids
myristic acid
lauric acid
Pseudomonas aeruginosa
quorum sensing
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2020.597517/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2020.597517/full

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