Orthosiphon stamineus Leaf Extract Affects TNF-α and Seizures in a Zebrafish Model

Orthosiphon stamineus Leaf Extract Affects TNF-α and Seizures in a Zebrafish Model

Epileptic seizures result from abnormal brain activity and can affect motor, autonomic and sensory function; as well as, memory, cognition, behavior, or emotional state. Effective anti-epileptic drugs (AEDs) are available but have tolerability issues due to their side effects. The Malaysian herb Ort...

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Bibliographic Details
Main Authors: Brandon Kar Meng Choo, Uday P. Kundap, Yatinesh Kumari, Seow-Mun Hue, Iekhsan Othman, Mohd Farooq Shaikh
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Pharmacology
Subjects:
epilepsy
Orthosiphon stamineus
zebrafish model
TNF-α
anticonvulsant activity
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00139/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2018.00139/full

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