A multi-labeled tree dissimilarity measure for comparing “clonal trees” of tumor progression
Abstract We introduce a new dissimilarity measure between a pair of “clonal trees”, each representing the progression and mutational heterogeneity of a tumor sample, constructed by the use of single cell or bulk high throughput sequencing data. In a clonal tree, each vertex represents a specific tum...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-07-01
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Series: | Algorithms for Molecular Biology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13015-019-0152-9 |