A Novel Mouse Model of Chronic Inflammatory and Overactive Bladder by a Single Intravesical Injection of Hydrogen Peroxide

Abstract.: There is so far no generally accepted animal model of chronic cystitis by which potential therapies can be evaluated. In this study, we aimed to establish a new mouse model of cystitis based on the proinflammatory effects of reactive oxygen species. A single intravesical injection of 1.5%...

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Bibliographic Details
Main Authors: Takashi Homan, Tetsunori Tsuzuki, Koji Dogishi, Hisashi Shirakawa, Tatsuya Oyama, Takayuki Nakagawa, Shuji Kaneko
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319303627