Fecal Host Transcriptomics for Non-invasive Human Mucosal Immune Profiling: Proof of Concept in Clostridium difficile Infection

Fecal Host Transcriptomics for Non-invasive Human Mucosal Immune Profiling: Proof of Concept in Clostridium difficile Infection

Background: Host factors play an important role in pathogenesis and disease outcome in Clostridium difficile infection (CDI), and characterization of these responses could uncover potential host biomarkers to complement existing microbe-based diagnostics. Methods: We extracted RNA from fecal sample...

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Bibliographic Details
Main Authors: Robert Schlaberg, Amanda Barrett, Kornelia Edes, Michael Graves, Litty Paul, Jenna Rychert, Bert K. Lopansri, Daniel T. Leung
Format: Article
Language:English
Published: Case Western Reserve University 2018-09-01
Series:Pathogens and Immunity
Subjects:
Clostridium difficile
host transcriptomics
fecal transcriptomics
actin-cytoskeleton
mucosal immune response
Online Access:http://paijournal.com/index.php/paijournal/article/view/250

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http://paijournal.com/index.php/paijournal/article/view/250

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