Glucokinase regulatory protein genetic variant interacts with omega-3 PUFA to influence insulin resistance and inflammation in metabolic syndrome.

Glucokinase Regulatory Protein (GCKR) plays a central role regulating both hepatic triglyceride and glucose metabolism. Fatty acids are key metabolic regulators, which interact with genetic factors and influence glucose metabolism and other metabolic traits. Omega-3 polyunsaturated fatty acids (n-3...

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Bibliographic Details
Main Authors: Pablo Perez-Martinez, Javier Delgado-Lista, Antonio Garcia-Rios, Jolene Mc Monagle, Hanne L Gulseth, Jose M Ordovas, Danielle I Shaw, Brita Karlström, Beata Kiec-Wilk, Ellen E Blaak, Olfa Helal, Małgorzata Malczewska-Malec, Catherine Defoort, Ulf Risérus, Wim H M Saris, Julie A Lovegrove, Christian A Drevon, Helen M Roche, Jose Lopez-Miranda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3108949?pdf=render