Efficacy Testing of H56 cDNA Tattoo Immunization against Tuberculosis in a Mouse Model

Efficacy Testing of H56 cDNA Tattoo Immunization against Tuberculosis in a Mouse Model

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a global threat. The only approved vaccine against TB, Mycobacterium bovis bacillus Calmette–Guérin (BCG), provides insufficient protection and, being a live vaccine, can cause disseminated disease in immunocompromised individual...

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Bibliographic Details
Main Authors: Anouk C. M. Platteel, Natalie E. Nieuwenhuizen, Teresa Domaszewska, Stefanie Schürer, Ulrike Zedler, Volker Brinkmann, Alice J. A. M. Sijts, Stefan H. E. Kaufmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Immunology
Subjects:
tuberculosis
vaccine
vaccination
DNA immunization
Mycobacterium bovis bacillus Calmette–Guérin
H56
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01744/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01744/full

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