Epilepsy in a melanocyte-lineage mTOR hyperactivation mouse model: A novel epilepsy model.

OBJECTIVE:To clarify the complex mechanism underlying epileptogeneis, a novel animal model was generated. METHODS:In our previous research, we have generated a melanocyte-lineage mTOR hyperactivation mouse model (Mitf-M-Cre Tsc2 KO mice; cKO mice) to investigate mTOR pathway in melanogenesis regulat...

Full description

Bibliographic Details
Main Authors: Fei Yang, Lingli Yang, Mari Wataya-Kaneda, Lanting Teng, Ichiro Katayama
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0228204