Epigenetic Modifications in Acute Myeloid Leukemia: Prognosis, Treatment, and Heterogeneity

Epigenetic Modifications in Acute Myeloid Leukemia: Prognosis, Treatment, and Heterogeneity

Leukemia, specifically acute myeloid leukemia (AML), is a common malignancy that can be differentiated into multiple subtypes based on leukemogenic history and etiology. Although genetic aberrations, particularly cytogenetic abnormalities and mutations in known oncogenes, play an integral role in AM...

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Bibliographic Details
Main Authors: Samantha L. Goldman, Ciaran Hassan, Mihir Khunte, Arielle Soldatenko, Yunji Jong, Ebrahim Afshinnekoo, Christopher E. Mason
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Genetics
Subjects:
acute myeloid leukemia
AML
epigenetics
heterogeneity
epialleles
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00133/full

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https://www.frontiersin.org/article/10.3389/fgene.2019.00133/full

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