Structural models for the design of novel antiviral agents against Greek Goat Encephalitis

Structural models for the design of novel antiviral agents against Greek Goat Encephalitis

The Greek Goat Encephalitis virus (GGE) belongs to the Flaviviridae family of the genus Flavivirus. The GGE virus constitutes an important pathogen of livestock that infects the goat’s central nervous system. The viral enzymes of GGE, helicase and RNA-dependent RNA polymerase (RdRP), are ideal targe...

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Bibliographic Details
Main Authors: Louis Papageorgiou, Styliani Loukatou, Vassiliki Lila Koumandou, Wojciech Makałowski, Vasileios Megalooikonomou, Dimitrios Vlachakis, Sophia Kossida
Format: Article
Language:English
Published: PeerJ Inc. 2014-11-01
Series:PeerJ
Subjects:
Greek Goat Encephalitis virus
Flaviviridae
RNA-dependent RNA polymerase
Homology modelling
Phylogenetic analysis
Drug design
Online Access:https://peerj.com/articles/664.pdf

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https://peerj.com/articles/664.pdf

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