Molecular profiles of response to neoadjuvant chemoradiotherapy in oesophageal cancers to develop personalized treatment strategies

Molecular profiles of response to neoadjuvant chemoradiotherapy in oesophageal cancers to develop personalized treatment strategies

Identification of molecular predictive markers of response to neoadjuvant chemoradiation could aid clinical decision‐making in patients with localized oesophageal cancer. Therefore, we subjected pretreatment biopsies of 75 adenocarcinoma (OAC) and 16 squamous cell carcinoma (OSCC) patients to target...

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Bibliographic Details
Main Authors: Leonie K. deKlerk, Ruben S. A. Goedegebuure, Nicole C. T. vanGrieken, Johanna W. vanSandick, Annemieke Cats, Jurrien Stiekema, Rosa T. van derKaaij, Arantza Farina Sarasqueta, Manon vanEngeland, Maarten A. J. M. Jacobs, Roy L. J. vanWanrooij, Donald L. van derPeet, Aaron R. Thorner, Henk M. W. Verheul, Victor L. J. L. Thijssen, Adam J. Bass, Sarah Derks
Format: Article
Language:English
Published: Wiley 2021-04-01
Series:Molecular Oncology
Subjects:
chemoradiation
DNA sequencing
gene methylation
genetic biomarkers
oesophageal cancer
predictive markers
Online Access:https://doi.org/10.1002/1878-0261.12907

Internet

https://doi.org/10.1002/1878-0261.12907

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