mLST8 Promotes mTOR-Mediated Tumor Progression.

The activity of the mechanistic target of rapamycin (mTOR) is elevated in various types of human cancers, implicating a role in tumor progression. However, the molecular mechanisms underlying mTOR upregulation remain unclear. In this study, we found that the expression of mLST8, a required subunit o...

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Bibliographic Details
Main Authors: Kyoko Kakumoto, Jun-Ichiro Ikeda, Masato Okada, Eiichi Morii, Chitose Oneyama
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4408021?pdf=render