Experimental Evaluation of Anticancer Efficiency and Acute Toxicity of Anthrafuran for Oral Administration

Experimental Evaluation of Anticancer Efficiency and Acute Toxicity of Anthrafuran for Oral Administration

The new antitumor agent anthrafuran has demonstrated a consistent effect in murine tumor models when administered parenterally due to the simultaneous inhibition of multiple cellular targets such as topoisomerases I/II and protein kinases. In this study, we assessed the anticancer efficiency and acu...

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Bibliographic Details
Main Authors: Andrey E. Shchekotikhin, Helen M. Treshalina, Michael I. Treshchalin, Eleonora R. Pereverzeva, Helen B. Isakova, Alexander S. Tikhomirov
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Pharmaceuticals
Subjects:
anthrafuran
antitumor activity
oral administration
acute toxicity
<i>LD</i><sub>50</sub>
Online Access:https://www.mdpi.com/1424-8247/13/5/81

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https://www.mdpi.com/1424-8247/13/5/81

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