The Antiproliferative Activity of Oxypeucedanin via Induction of G<sub>2</sub>/M Phase Cell Cycle Arrest and p53-Dependent MDM2/p21 Expression in Human Hepatoma Cells

Oxypeucedanin (OPD), a furocoumarin compound from <i>Angelica dahurica</i> (Umbelliferae), exhibits potential antiproliferative activities in human cancer cells. However, the underlying molecular mechanisms of OPD as an anticancer agent in human hepatocellular cancer cells have not been...

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Bibliographic Details
Main Authors: So Hyun Park, Ji-Young Hong, Hyen Joo Park, Sang Kook Lee
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Molecules
Subjects:
p53
Online Access:https://www.mdpi.com/1420-3049/25/3/501