Extrastriatal dopaminergic abnormalities of DA homeostasis in Parkinson's patients with medication-induced pathological gambling: A [11C] FLB-457 and PET study

Extrastriatal dopaminergic abnormalities of DA homeostasis in Parkinson's patients with medication-induced pathological gambling: A [11C] FLB-457 and PET study

Impulse control disorders such as pathological gambling (PG) are a serious and common adverse effect of dopamine (DA) replacement medication in Parkinson's disease (PD). Patients with PG have increased impulsivity and abnormalities in striatal DA, in common with behavioural and substance addict...

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Bibliographic Details
Main Authors: Nicola J. Ray, Janis M. Miyasaki, Mateusz Zurowski, Ji Hyun Ko, Sang Soo Cho, Giovanna Pellecchia, Francesca Antonelli, Sylvain Houle, Anthony E. Lang, Antonio P. Strafella
Format: Article
Language:English
Published: Elsevier 2012-12-01
Series:Neurobiology of Disease
Subjects:
Parkinson's disease
Dopamine agonists
Pathological gambling
Impulsivity
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996112002367

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http://www.sciencedirect.com/science/article/pii/S0969996112002367

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