Soluble cytotoxic T-lymphocyte–associated antigen 4 (sCTLA-4) as a potential biomarker for diagnosis and evaluation of the prognosis in Glioma

Soluble cytotoxic T-lymphocyte–associated antigen 4 (sCTLA-4) as a potential biomarker for diagnosis and evaluation of the prognosis in Glioma

Abstract Background The cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) is widely considered as a pivotal immune checkpoint molecule to suppress antitumor immunity. However, the significance of soluble CTLA-4 (sCTLA-4) remains unclear in the patients with brain glioma. Here we aimed to investig...

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Bibliographic Details
Main Authors: Jiajia Liu, Xiaoyi Tian, Yan Wang, Xixiong Kang, Wenqi Song
Format: Article
Language:English
Published: BMC 2021-05-01
Series:BMC Immunology
Subjects:
Soluble cytotoxic T-lymphocyte antigen 4(sCTLA-4)
Glioma
Biomarker
Prognosis
Online Access:https://doi.org/10.1186/s12865-021-00422-y

Internet

https://doi.org/10.1186/s12865-021-00422-y

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