Generation of GADD45A gene knockout human embryonic stem cell line using CRISPR/Cas9

Generation of GADD45A gene knockout human embryonic stem cell line using CRISPR/Cas9

GADD45A is a DNA damage and stressful growth arrest inducible protein, also it is shown to a be tumor suppressor gene and a chromatin relaxer associated with opening chromatin during the somatic reprogramming. However, its role in human embryonic stem cells and human embryonic stem cell modeled deve...

Full description

Bibliographic Details
Main Authors: Jinbing Li, Yuhang Li, Xiao-Yong Zhan, Xinru Ran, Hung-Fat Tse, Shiying Dang, Yichu Nie, Ke Huang
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506120303913

Internet

http://www.sciencedirect.com/science/article/pii/S1873506120303913

Similar Items