QiShenYiQi ameliorates salt-induced hypertensive nephropathy by balancing ADRA1D and SIK1 expression in Dahl salt-sensitive rats

QiShenYiQi ameliorates salt-induced hypertensive nephropathy by balancing ADRA1D and SIK1 expression in Dahl salt-sensitive rats

Background: Hypertension is a leading risk factor for developing kidney disease. Current single-target antihypertensive drugs are not effective for hypertensive nephropathy, in part due to its less understood mechanism of pathogenesis. We recently showed that QiShenYiQi (QSYQ), a component-based car...

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Bibliographic Details
Main Authors: Hongxia Du, Guangxu Xiao, Zhifeng Xue, Zhixiong Li, Shuang He, Xiaoli Du, Zhengchan Zhou, Linghua Cao, Yule Wang, Jian Yang, Xiaoying Wang, Yan Zhu
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Biomedicine & Pharmacotherapy
Subjects:
QiShenYiQi
Salt-sensitive hypertension
Kidney injury
Alpha-1D adrenergic receptor
Salt inducible kinase 1
Online Access:http://www.sciencedirect.com/science/article/pii/S075333222100723X

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http://www.sciencedirect.com/science/article/pii/S075333222100723X

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