MMP2-cleavage of DMP1 generates a bioactive peptide promoting differentiation of dental pulp stem/progenitor cell

Dentin Matrix Protein 1 (DMP1) plays a regulatory role in dentin mineralization and can also function as a signaling molecule. MMP-2 (matrix metalloproteinase-2) is a predominant protease in the dentin matrix that plays a prominent role in tooth formation and a potential role during the carious proc...

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Bibliographic Details
Main Authors: C Chaussain, AS Eapen, E Huet, C Floris, S Ravindran, J Hao, S Menashi, A George
Format: Article
Language:English
Published: AO Research Institute Davos 2009-11-01
Series:European Cells & Materials
Subjects:
Online Access:http://www.ecmjournal.org/journal/papers/vol018/vol018a08.php