Probing the operability regime of an engineered ribocomputing unit in terms of dynamic range maintenance with extracellular changes and time

Abstract Synthetic biology aims at engineering gene regulatory circuits to end with cells (re)programmed on purpose to implement novel functions or discover natural behaviors. However, one overlooked question is whether the resulting circuits perform as intended in variety of environments or with ti...

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Bibliographic Details
Main Authors: Roser Montagud-Martínez, Jordi Ventura, Rafael Ballesteros-Garrido, Arantxa Rosado, Guillermo Rodrigo
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Journal of Biological Engineering
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13036-020-00234-5