Hesperidin improves insulin resistance via down-regulation of inflammatory responses: Biochemical analysis and in silico validation.

Hesperidin improves insulin resistance via down-regulation of inflammatory responses: Biochemical analysis and in silico validation.

Leptin resistance and co-existing insulin resistance is considered as hallmark of diet-induced obesity. Here, we investigated therapeutic potential of hesperidin to improve leptin and insulin resistance using high fat diet (HFD)-induced obese experimental animal model. We also performed in silico st...

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Bibliographic Details
Main Authors: Kanwal Rehman, Syeda Mehak Munawar, Muhammad Sajid Hamid Akash, Manal Ali Buabeid, Tahir Ali Chohan, Muhammad Tariq, Komal Jabeen, El-Shaimaa A Arafa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0227637

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https://doi.org/10.1371/journal.pone.0227637

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