Performance of Web tools for predicting changes in protein stability caused by mutations

Performance of Web tools for predicting changes in protein stability caused by mutations

Abstract Background Despite decades on developing dedicated Web tools, it is still difficult to predict correctly the changes of the thermodynamic stability of proteins caused by mutations. Here, we assessed the reliability of five recently developed Web tools, in order to evaluate the progresses in...

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Bibliographic Details
Main Authors: Anna Marabotti, Eugenio Del Prete, Bernardina Scafuri, Angelo Facchiano
Format: Article
Language:English
Published: BMC 2021-07-01
Series:BMC Bioinformatics
Subjects:
Protein mutations
Protein stability
Rare diseases
Predictions
Statistical analysis
Online Access:https://doi.org/10.1186/s12859-021-04238-w

Internet

https://doi.org/10.1186/s12859-021-04238-w

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