RNA binding protein HuR regulates the expression of ABCA1[S]

RNA binding protein HuR regulates the expression of ABCA1[S]

ABCA1 is a major regulator of cellular cholesterol efflux and plasma HDL biogenesis. Even though the transcriptional activation of ABCA1 is well established, the posttranscriptional regulation of ABCA1 expression is poorly understood. Here, we investigate the potential contribution of the RNA bindin...

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Bibliographic Details
Main Authors: Cristina M. Ramírez, Chin Sheng Lin, Kotb Abdelmohsen, Leigh Goedeke, Je-Hyun Yoon, Julio Madrigal-Matute, Jose L. Martin-Ventura, Dat T. Vo, Philip J. Uren, Luiz O. Penalva, Myriam Gorospe, Carlos Fernández-Hernando
Format: Article
Language:English
Published: Elsevier 2014-06-01
Series:Journal of Lipid Research
Subjects:
ATP binding cassette transporter A1
human antigen R
posttranscriptional regulation
lipid homeostasis
cholesterol efflux
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520352706

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http://www.sciencedirect.com/science/article/pii/S0022227520352706

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