Early dysregulation of cardiac-specific microRNA-208a is linked to maladaptive cardiac remodelling in diabetic myocardium

Early dysregulation of cardiac-specific microRNA-208a is linked to maladaptive cardiac remodelling in diabetic myocardium

Abstract Background The diabetic heart undergoes remodelling contributing to an increased incidence of heart failure in individuals with diabetes at a later stage. The molecular regulators that drive this process in the diabetic heart are still unknown. Methods Real-time (RT) PCR analysis was perfor...

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Bibliographic Details
Main Authors: Shruti Rawal, Prashanth Thevakar Nagesh, Sean Coffey, Isabelle Van Hout, Ivor F. Galvin, Richard W. Bunton, Philip Davis, Michael J. A. Williams, Rajesh Katare
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Cardiovascular Diabetology
Subjects:
Diabetic heart disease
microRNA
Cardiac hypertrophy
Modulation of microRNA
Online Access:http://link.springer.com/article/10.1186/s12933-019-0814-4

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http://link.springer.com/article/10.1186/s12933-019-0814-4

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