Refining the diagnosis of Huntington Disease: The PREDICT-HD study

Participants with the gene expansion for Huntington disease (HD) but not yet diagnosed were evaluated annually. Unidimensional diagnosis (UD) was a motor diagnosis defined as a diagnostic confidence level (DCL) of 4 (unequivocal motor signs, ≥99% confidence) on the standardized motor exam of the Uni...

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Bibliographic Details
Main Authors: Kevin M Biglan, Ying eZhang, Jeffery eLong, Michael eGeschwind, Gail eKang, Annie eKilloran, Wenjing eLu, Elizabeth eMcCusker, James A Mills, Lynn A Raymond, Claudia eTesta, Joanne eWojcieszek, Jane S Paulsen
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-04-01
Series:Frontiers in Aging Neuroscience
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Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2013.00012/full