Fast design of arbitrary length loops in proteins using InteractiveRosetta

Fast design of arbitrary length loops in proteins using InteractiveRosetta

Abstract Background With increasing interest in ab initio protein design, there is a desire to be able to fully explore the design space of insertions and deletions. Nature inserts and deletes residues to optimize energy and function, but allowing variable length indels in the context of an interact...

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Bibliographic Details
Main Authors: William F. Hooper, Benjamin D. Walcott, Xing Wang, Christopher Bystroff
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Bioinformatics
Subjects:
Indel
Bystroff
InteractiveRosetta
Rosetta
PyRosetta
T7 endonuclease I
Online Access:http://link.springer.com/article/10.1186/s12859-018-2345-5

Internet

http://link.springer.com/article/10.1186/s12859-018-2345-5

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