Cell-autonomous light sensitivity via Opsin3 regulates fuel utilization in brown adipocytes.

Cell-autonomous light sensitivity via Opsin3 regulates fuel utilization in brown adipocytes.

Opsin3 (Opn3) is a transmembrane heptahelical G protein-coupled receptor (GPCR) with the potential to produce a nonvisual photoreceptive effect. Interestingly, anatomical profiling of GPCRs reveals that Opn3 mRNA is highly expressed in adipose tissue. The photosensitive functions of Opn3 in mammals...

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Bibliographic Details
Main Authors: Mari Sato, Tadataka Tsuji, Kunyan Yang, Xiaozhi Ren, Jonathan M Dreyfuss, Tian Lian Huang, Chih-Hao Wang, Farnaz Shamsi, Luiz O Leiria, Matthew D Lynes, King-Wai Yau, Yu-Hua Tseng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-02-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000630

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https://doi.org/10.1371/journal.pbio.3000630

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