An In Vitro/In Vivo Model to Analyze the Effects of Flubendazole Exposure on Adult Female Brugia malayi.

Current control strategies for onchocerciasis and lymphatic filariasis (LF) rely on prolonged yearly or twice-yearly mass administration of microfilaricidal drugs. Prospects for near-term elimination or eradication of these diseases would be improved by availability of a macrofilaricide that is high...

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Bibliographic Details
Main Authors: Maeghan O'Neill, Abdelmoneim Mansour, Utami DiCosty, James Geary, Michael Dzimianski, Scott D McCall, John W McCall, Charles D Mackenzie, Timothy G Geary
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-05-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4856366?pdf=render