Neuroblastoma Risk Assessment and Treatment Stratification with Hybrid Capture-Based Panel Sequencing

Neuroblastoma Risk Assessment and Treatment Stratification with Hybrid Capture-Based Panel Sequencing

For many years, the risk-based therapy stratification of children with neuroblastoma has relied on clinical and molecular covariates. In recent years, genome analysis has revealed further alterations defining risk, tumor biology, and therapeutic targets. The implementation of a robust and scalable m...

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Bibliographic Details
Main Authors: Annabell Szymansky, Louisa-Marie Kruetzfeldt, Lukas C. Heukamp, Falk Hertwig, Jessica Theissen, Hedwig E. Deubzer, Eva-Maria Willing, Roopika Menon, Steffen Fuchs, Theresa Thole, Stefanie Schulte, Karin Schmelz, Annette Künkele, Peter Lang, Jörg Fuchs, Angelika Eggert, Cornelia Eckert, Matthias Fischer, Anton G. Henssen, Elias Rodriguez-Fos, Johannes H. Schulte
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Journal of Personalized Medicine
Subjects:
neuroblastoma
hybrid capture panel sequencing
<i>MYCN</i>
<i>ALK</i>
risk stratification
targeted therapies
Online Access:https://www.mdpi.com/2075-4426/11/8/691

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https://www.mdpi.com/2075-4426/11/8/691

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