Tumor protein 53-induced nuclear protein 1 (TP53INP1) enhances p53 function and represses tumorigenesis

Tumor protein 53-induced nuclear protein 1 (TP53INP1) is a stress-induced p53 target gene whose expression is modulated by transcription factors such as p53, p73 and E2F1. TP53INP1 gene encodes two isoforms of TP53INP1 proteins, TP53INP1α and TP53INP1β, both of which appear to be key elements in p53...

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Bibliographic Details
Main Authors: Jeyran eShahbazi, Richard eLock, Tao eLiu
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-05-01
Series:Frontiers in Genetics
Subjects:
p53
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00080/full