Bmp and Shh signaling mediate the expression of satb2 in the pharyngeal arches.

In human, mutation of the transcription factor SATB2 causes severe defects to the palate and jaw. The expression and sequence of SATB2 is highly conserved across vertebrate species, including zebrafish. We sought to understand the regulation of satb2 using the zebrafish model system. Due to the norm...

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Bibliographic Details
Main Authors: Kelly Sheehan-Rooney, Mary E Swartz, C Ben Lovely, Michael J Dixon, Johann K Eberhart
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3605343?pdf=render