Effects of Iron-Oxide Nanoparticle Surface Chemistry on Uptake Kinetics and Cytotoxicity in CHO-K1 Cells

Effects of Iron-Oxide Nanoparticle Surface Chemistry on Uptake Kinetics and Cytotoxicity in CHO-K1 Cells

Superparamagnetic iron-oxide nanoparticles (SPIONs) show great promise for multiple applications in biomedicine. While a number of studies have examined their safety profile, the toxicity of these particles on reproductive organs remains uncertain. The goal of this study was to evaluate the cytotoxi...

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Bibliographic Details
Main Authors: Camille C. Hanot, Young Suk Choi, Tareq B. Anani, Dharsan Soundarrajan, Allan E. David
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:International Journal of Molecular Sciences
Subjects:
superparamagnetic iron-oxide nanoparticles (SPIONs)
PEGylated nanoparticles
aminated nanoparticles
reproductive toxicity
nanotoxicity
uptake kinetics
ROS generation
Online Access:http://www.mdpi.com/1422-0067/17/1/54

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http://www.mdpi.com/1422-0067/17/1/54

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