Icariside II attenuates lipopolysaccharide-induced neuroinflammation through inhibiting TLR4/MyD88/NF-κB pathway in rats

Icariside II attenuates lipopolysaccharide-induced neuroinflammation through inhibiting TLR4/MyD88/NF-κB pathway in rats

Inflammation in central nervous system (CNS) plays a vital role in neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), Lewy body dementia (DLB), HIV-related dementia and traumatic brain injury. Icariside II (ICS II), an active flavonoid compound derived f...

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Bibliographic Details
Main Authors: Jiayin Zhou, Yuanyuan Deng, Fei Li, Caixia Yin, Jingshan Shi, Qihai Gong
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Icariside II
Lipopolysaccharide
Neuroinflammation
Toll-like 4
Brain
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218345815

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http://www.sciencedirect.com/science/article/pii/S0753332218345815

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